Crystal structure of non-fused glutathione S-transferase from Schistosoma japonicum in complex with glutathione |
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| Authors: | Kursula I Heape A M Kursula P |
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| Institution: | Department of Biochemistry, Biocenter Oulu, Oulu University, Oulu, Finland. |
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| Abstract: | Schistosoma japonicum glutathione S-transferase (SjGST) is a common fusion tag in recombinant protein production, and its 3-dimensional structure has been studied in the context of drug design. We have determined the crystal structure of non-fused SjGST complexed with glutathione, and compare it to complexes between glutathione and SjGST fusion proteins. |
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