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Phaeohyphomycosis Caused by Chaetomium Globosum in an Allogeneic Bone Marrow Transplant Recipient
Authors:Teixeira  ABA  Trabasso  P  Moretti-Branchini  ML  Aoki  FH  Vigorito  AC  Miyaji  M  Mikami  Y  Takada  M  Schreiber  AZ
Institution:Clinical Pathology Department, Universidade Estadual de Campinas-UNICAMP, Brazil.
Abstract:Bone marrow transplant recipients are highly susceptible to opportunistic fungal infections. This is the report, of the first case of a Chaetomium systemic infection described in Brazil. A 34 year-old patient with chronic myeloid leukemia underwent an allogeneic sibling matched bone marrow transplant. Seven months later, he developed systemic infection with enlargement of the axillary and cervical lymph nodes. Culture of the aspirates from both lymph nodes yielded Chaetomium globosum. The infection was successfully treated with amphotericin B. The increasing population of immunosupressed patients requires a careful microbiologic investigation for uncommon fungal infections.
Keywords:Amphotericin B  bone marrow transplant  Chaetomium globosum  phaeohyphomycosis
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