| Abstract: | It was shown that 9 strains of P. mallei were sensitive to sulfanilamides and their combinations with trimethoprim: sulfamonomethoxine + trimethoprim (2.5:1), sulfamethoxazole + trimethoprim (5:1) and sulfazin + trimethoprim (2.5:1 and 5:1). In regard to multiple lowering of the minimum bactericidal concentration of both drugs the combinations of sulfazin with trimethoprim (5:1 or 2.5:1) and sulfamethoxazole with trimethoprim (5:1) or biseptol proved to be the most active. The activity of the sulfamonomethoxine combination with trimethoprim (sulfate) was lower. |
