4-phenyldiazenyl 2-(phenylimino methyl) phenols; synthesis and in-vitro biological evaluation as potential antibacterial agents |
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Authors: | Halve Anand K Dubey Pushp Kant Kankoriya Amit Tiwari Kiran |
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Affiliation: | School of Studies in Chemistry, Jiwaji University Gwalior - 474011, India. halveanand@yahoo.co.in |
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Abstract: | A new series of 4-phenyldiazenyl 2-(phenylimino methyl) phenols were synthesized by the condensation of 5-[(2-chloro phenyl) diazenyl] 2-hydroxybenzaldehyde with different substituted aromatic amines and sulphonamides. All the synthesized compounds were screened in-vitro for their antibacterial activity against different human pathogens viz: B. anthracis, E.coli, S. aureus, S. typhimurium, and P. aeruginosa using disk diffusion assay. All the compounds exhibited considerable inhibition against the bacteria tested. |
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