Growth and Carcass Composition in Broiler-Type Chickens Following Passive Immunization of Insulin-Like Growth Factor-2 (IGF-2) Between 2 and 4 Weeks of Age |
| |
Institution: | 2. Henan Key Laboratory for Innovation and Utilization of Chicken Germplasm Resources, Zhengzhou 450046, China;3. International Joint Research Laboratory for Poultry Breeding of Henan, Zhengzhou 450046, China |
| |
Abstract: | Ten broiler-type chickens at 2 weeks of age were injected daily with 0.5 ml of normal sheep serum while 10 others were similarly injected with 0.5 ml of a sheep anti-IGF-2 serum. Immunization with anti-IGF-2 serum had no significant effect upon body weight gain, on carcass composition, on appetite or food conversion. Liver weight was significantly increased (P < 0.05) in the anti-IGF-2 birds, but there was no effect on the weight of any other organ measured. The proportion of breast muscle in the carcass of anti-IGF-2 treated birds was significantly lower (P < 0.01) than in the controls and they also had 27% less abdominal fat. In acute studies, anti-IGF-2 administration caused an elevation in plasma GH, but in the longer term neither plasma GH nor plasma T3 concentrations were significantly affected by immunization against IGF-2. These results suggest that circulating IGF-2 is not a major regulator of overall somatic growth in chickens, but may have an effect on muscle and fat deposition. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|