Naturally occurring cancer-associated mutations disrupt oligomerization and activity of protein arginine methyltransferase 1 (PRMT1) |
| |
| Authors: | Owen M. Price Abhishek Thakur Ariana Ortolano Arianna Towne Caroline Velez Orlando Acevedo Joan M. Hevel |
| |
| Affiliation: | 1.Department of Chemistry and Biochemistry, Utah State University, Logan, Utah, USA;2.Department of Chemistry, University of Miami, Coral Gables, Florida, USA |
| |
| Abstract: | |
| |
| Keywords: | arginine methylation, enzyme mutation, molecular dynamics, oligomerization, posttranslational modification (PTM), structure– function, signaling, dimerization, protein arginine methyltransferase, PRMT1 |
|
|
