Chromatographic separation of putative precursors of cholestanol |
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| Authors: | A K Batta G Salen S Shefer |
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| Institution: | Department of Medicine, UMDNJ-New Jersey Medical School, Newark 07103. |
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| Abstract: | This paper describes convenient syntheses for labeled and unlabeled cholest-5-en-3-one, cholest-4-en-3-one, epicholesterol, cholest-4-en-3 beta-ol, and cholest-4-en-3 alpha-ol. The thin-layer chromatography, high-performance liquid chromatography, and gas-liquid chromatography of these compounds and of cholestanol and epicholestanol are also described. The synthesized compounds are potential precursors in the biosynthesis of cholestanol in mammals. |
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