| 云南辛德毕斯病毒的生物学性状研究 |
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| 引用本文： | 黄文丽,周国林,等.云南辛德毕斯病毒的生物学性状研究[J].Virologica Sinica,2001,16(2):97-100. |
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| 作者姓名： | 黄文丽 周国林 |
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| 作者单位： | [1]云南省流行病防治研究所，云南大理市671000 [2]中国预防医学科学院病毒学研究所，北京100052 |
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| 摘 要： | 本文对云南首次分离到的Sindbis病毒进行了滤过试验，耐酸耐醚试验、致细胞病变、动物敏感性试验、血压 凝特性、空斑和毒力等试验研究，结果符合披膜病毒科的病毒特性。交 因抑试验和免疫荧光试验，以及空斑减小中和试验进一步证实为甲病毒属的Sindbis病毒，其空斑纯化株的生物学特性也与原株相符，纯化株的制备为该株病毒分子生物学研究的准确性和一致性提供了条件。云南Sindbis病毒的首次分离具有重要的流行病学意义，其生物学特性研究结果对我省该病的诊断和防治具有重要的指导意义。
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| 关 键 词： | 辛德毕斯病毒 生物学特性 空斑纯化 云南 |
Study on Biological Characters of Sindbis Virus Yunnan Strain |
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| HUANG Wen li ,ZHANG Hai lin ,WANG Jing lin ,ZHANG Yu zeng ,ZHOU Guo lin ,MI Zhu qin ,SHI Hua fang ,ZI Deng yun ,LIAN Guo dong.Study on Biological Characters of Sindbis Virus Yunnan Strain[J].中国病毒学(英文版),2001,16(2):97-100. |
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| Authors: | HUANG Wen li ZHANG Hai lin WANG Jing lin ZHANG Yu zeng ZHOU Guo lin MI Zhu qin SHI Hua fang ZI Deng yun LIAN Guo dong |
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| Institution: | HUANG Wen li 1,ZHANG Hai lin 1,WANG Jing lin 1,ZHANG Yu zeng 1,ZHOU Guo lin 2,MI Zhu qin 1,SHI Hua fang 1,ZI Deng yun 1,LIAN Guo dong 2 |
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| Abstract: | The biological characters of Sindbis virus strain of Yunnan(YN87448 strain) were studied by the test of the filtration, acid resistant, ether resistant, CPE, susceptibility of animal, HA, plague, determination of virus titres, and the cross HI, cross IFAT and PRNT as well.The results indicated that YN87448 strain belongs to Sindbis virus, Alphavirus, Togaviridae. YN87448 strain virus was plaque purified(PYN87448). The biological character of PYN87448 strain virus was studied too. PYN87448 strain virus will be used in the molecule biological test. |
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| Keywords: | Sindbis virus Biological character Plaque purify |
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