Seasonal Variation in Urinary Excretion of Calcium, Magnesium and Phosphate in Manic-Melancholic Patients |
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Authors: | Birgitta Mellerup Erling T. Mellerup |
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Affiliation: | a University Library, Scientific and Medical Dept, Copenhagen, Denmarkb Psychochemistry Institute, Rigshospitalet, Copenhagen, Denmark |
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Abstract: | The 24-hr urinary excretion of calcium, magnesium and phosphate was measured in 76 normal control persons, 95 manic-melancholic patients not on lithium treatment and 74 lithium-treated manic-melancholic patients. The mean value of the urinary excretion for each of the four seasons during a 5-year period was calculated. The normal control persons had a higher excretion of calcium during the summer months than during the rest of the year; this seasonal variation was not present in the two groups of manic-melancholic patients.
Previously reported changes in electrolyte metabolism during lithium treatment were confirmed, but some of the results varied with the season. |
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Keywords: | Seasonal variation urinary excretion calcium magnesium phosphate manic-melancholic patients lithium |
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