The evolutionary trajectory of mitochondrial carrier family during metazoan evolution |
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Authors: | Ming Gong Jie Li Meng Wang Jin Wang Ke Zen Chen-Yu Zhang |
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Affiliation: | (1) Jiangsu Diabetes Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, 210093 Nanjing, Jiangsu, China |
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Abstract: | Background Exploring metabolic evolution is a way to understand metabolic complexity. The substrate transport of mitochondrial carrier family (MCF) influences direct metabolic activities, making it possible to understand indirectly metabolic evolution from the evolution of substrate transport of MCF. However, the evolutionary study of substrate transport of MCF does not mean that all the concrete structures of mitochondrial carriers (MCs) must first be gained. |
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