Toll-like receptors and fungal infections: the role of TLR2, TLR4 and MyD88 in paracoccidioidomycosis |
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| Authors: | Calich Vera L G Pina Adriana Felonato Maíra Bernardino Simone Costa Tania A Loures Flávio V |
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| Institution: | Departamento de Imunologia, Instituto de Ciências Biomédicas, Universidade de S?o Paulo, S?o Paulo, SP, Brazil. vlcalich@icb.usp.br |
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| Abstract: | The aim of this minireview is to present a concise view of the most important pattern recognition receptors used by the innate immune system to sense and control pathogen growth into host tissues. A brief review of the role of Toll-like receptors (TLRs) in fungal infections followed by some recent results on the function of TLR4, TLR2 and the MyD88 adaptor molecule in the pathogenesis of paracoccidioidomycosis are presented. |
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| Keywords: | toll-like receptors fungal pathogens paracoccidioidomycosis TLR2 TLR4 MyD88 |
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