Studies on Cardiotonic Substances Produced by Microorganisms. (I) |
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| Authors: | Masatoshi Umeda Heiichi Sakai Kei Arima Ryuta Ito |
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| Institution: | Department of Agricultural Chemistry, Faculty of Agriculture, University of Tokyo |
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| Abstract: | The active substances such as cardiotonics or toxics which were produced in the cultured broths or contained in the mycellia of microorganisms were examined by Ito’s assay method for cardiotonica using the embryonic heart of Japanese killi-fish.There were some strains obtained from actinomycetes whose cultured broths or methanol mycelial extracts showed these activities, but fewer from moulds, yeasts and bacteria. |
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