Multienzyme complexes of eukaryotic aminoacyl-tRNA synthetases |
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| Authors: | Chuan V Dang Chi V Dang |
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| Institution: | (1) Department of Biochemistry, School of Medicine, Loma Linda University, 92350 Loma Linda, California, USA;(2) Department of Medicine, Johns Hopkins University, School of Medicine, 21205 Baltimore, Maryland, USA |
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| Abstract: | Eukaryotic aminoacyl-tRNA synthetases, unlike their prokaryotic counterparts, may occur as high-Mr multienzyme complexes. Recently, successful purification of synthetase complexes makes possible the elucidation of the structural organization of these high-Mr complexes. Although their physiological significance remains unknown, recent studies suggest some possible functional roles for these complexes. |
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