| 医用钕铁硼体内植入表面改性研究现状* |
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| 引用本文： | 刘 豪,付 珊,付琴琴,马思捷,张砚超,邱明龙,马 锋,安英凤,史爱华,田波彦,张 曼,吕 毅,严小鹏. 医用钕铁硼体内植入表面改性研究现状*[J]. 现代生物医学进展, 2019, 19(1): 175-179 |
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| 作者姓名： | 刘 豪 付 珊 付琴琴 马思捷 张砚超 邱明龙 马 锋 安英凤 史爱华 田波彦 张 曼 吕 毅 严小鹏 |
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| 作者单位： | 西安交通大学第一附属医院肝胆外科;精准外科与再生医学国家地方联合工程研究中心;西安交通大学医学部启德书院;西安交通大学金属材料强度国家重点实验室;陕西省疾病预防控制中心 |
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| 基金项目： | 陕西省自然科学基础研究计划项目（2017JQ8021）；国家自然科学基金项目（81700545） |
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| 摘 要： | 随着磁外科相关技术的不断深入研究和临床探索应用,钕铁硼磁体体内植入需求不断增加,对于植入人体的磁体表面要求也不断提高。由于人体不同植入部位生理环境不同,对表面改性的要求也不同。目前钕铁硼磁性材料体内植入表面改性方法多样,但用于人体内不同部位的表面改性效果尚不确切,且缺乏系统的评价。该文详细总结了现有医用钕铁硼磁体表面改性方法,针对现阶段表面改性存在的问题提出总结,以期为后续研究提供思路和方向。
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| 关 键 词： | 磁外科；钕铁硼；表面改性 |
| 收稿时间： | 2018-04-18 |
| 修稿时间： | 2018-06-13 |
Research Status of Medical NdFeB Implantation Surface Modification* |
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| LIU Hao,FU Shan,FU Qin-qin,MA Si-jie,ZHANG Yan-chao,QIU Ming-long,MA Feng,AN Ying-feng,SHI Ai-hu,TIAN Bo-yan,ZHANG Man,LV Yi and YAN Xiao-peng. Research Status of Medical NdFeB Implantation Surface Modification*[J]. Progress in Modern Biomedicine, 2019, 19(1): 175-179 |
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| Authors: | LIU Hao FU Shan FU Qin-qin MA Si-jie ZHANG Yan-chao QIU Ming-long MA Feng AN Ying-feng SHI Ai-hu TIAN Bo-yan ZHANG Man LV Yi YAN Xiao-peng |
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| Affiliation: | 1 Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi''an Jiaotong University, Xi''an, Shaanxi, 710061, China;2 National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Xi''an, Shaanxi, 710061, China;3 Qide College, Xi''an Jiaotong University Health Science Center, Xi''an, Shaanxi, 710061, China,1 Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi''an Jiaotong University, Xi''an, Shaanxi, 710061, China;2 National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Xi''an, Shaanxi, 710061, China;3 Qide College, Xi''an Jiaotong University Health Science Center, Xi''an, Shaanxi, 710062, China,National key laboratory of metal material strength of Xi''an Jiaotong University, Xi''an, Shaanxi, 710049, China,1 Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi''an Jiaotong University, Xi''an, Shaanxi, 710061, China;2 National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Xi''an, Shaanxi, 710061, China;3 Qide College, Xi''an Jiaotong University Health Science Center, Xi''an, Shaanxi, 710061, China,1 Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi''an Jiaotong University, Xi''an, Shaanxi, 710061, China;2 National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Xi''an, Shaanxi, 710061, China;3 Qide College, Xi''an Jiaotong University Health Science Center, Xi''an, Shaanxi, 710062, China,1 Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi''an Jiaotong University, Xi''an, Shaanxi, 710061, China;2 National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Xi''an, Shaanxi, 710061, China;3 Qide College, Xi''an Jiaotong University Health Science Center, Xi''an, Shaanxi, 710063, China,National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Xi''an, Shaanxi, 710061, China,2National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Xi''an, Shaanxi, 710061, China; 5 Shaanxi Provincial Centre for Disease Control and Prevention, Xi''an, Shaanxi, 710054, China,National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Xi''an, Shaanxi, 710061, China,Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi''an Jiaotong University, Xi''an, Shaanxi, 710061, China,Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi''an Jiaotong University, Xi''an, Shaanxi, 710062, China,1 Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi''an Jiaotong University, Xi''an, Shaanxi, 710061, China;2 National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Xi''an, Shaanxi, 710061, China and 1 Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi''an Jiaotong University, Xi''an, Shaanxi, 710061, China;2 National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Xi''an, Shaanxi, 710062, China |
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| Abstract: | ABSTRACT: With the continuous in-depth research and clinical exploration of related technologies in magnetic surgery, the demand for implanting NdFeB magnets has been increasing, and the surface requirements for the magnets implanted into the human body have also been continuously improved. Because of the different physiological environments of different implantation sites in the human body, the requirements for surface modification are also different. At present, the surface modification methods of NdFeB magnetic materials implanted in vivo are various, but the effect of surface modification in different parts of the human body is not yet definitive, and the lack of systematic evaluation. In this paper, the implanted environment and a variety of surface modification methods of the existing medical NdFeB magnets are summarized in detail. The problems existing in the surface modification at the current stage are summarized in order to provide ideas and directions for follow-up study. |
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| Keywords: | Magnetic surgery NdFeB Surface modified |
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