舒芬太尼术后镇痛对剖宫产后产妇血清儿茶酚胺、泌乳素水平及血流动力学的影响

目的:探讨舒芬太尼术后镇痛对剖宫产术后产妇血清儿茶酚胺(CA)、泌乳素(PRL)水平及血流动力学的影响。方法:选择我院2015年1月～2016年12月收治的98例剖宫术产妇,术后按不同镇痛方式分为对照组与研究组,每组49例。对照组予以芬太尼镇痛,研究组予以舒芬太尼镇痛。观察并比较两组治疗前后血清多巴胺、去甲肾上腺素、肾上腺素、PRL、心率及平均动脉压水平的变化,镇痛效果及不良反应的发生情况。结果:手术后,两组血清多巴胺、去甲肾上腺素、肾上腺素、PRL、心率、平均动脉压、VAS水平均较手术前显著上升,且研究组以上指标均显著低于对照组(P0.05)。研究组不良反应发生率显著低于对照组(P0.05)。结论:舒芬太尼用于剖宫产术后的镇痛效果肯定,能够抑制产妇术后CA的分泌,且对泌乳及血流动力学的影响较小。

Effects of Postoperative Analgesia by Sufentanil on the Level of Catecholamine and Prolactin and Hemodynamics of Maternal after Cesarean Section

ABSTRACT Objective: To discuss the effects of the postoperative analgesia on the serum levels of catecholamine, prolactin and hemodynamics and lactation of patients after the cesarean section maternal. Methods: 98 cases of cesarean section maternal from January 2015 to December 2016 were selected and according to different analgesia methods, the patients were divided into the control group and the research group. Then the dopamine, norepinephrine, epinephrine, plasma PRL, visual analogue scale (VAS), heart rate and mean arterial pressure, and incidence of adverse reactions were observed and compared between the two groups before and after the treatment. Results: After surgery, the dopamine, norepinephrine, epinephrine, plasma PRL, heart rate, mean arterial pressure and VAS in the two groups were significantly lower than before, and the research group was significantly lower than that of the control group, and the differences were statistically significant (P<0.05). There was no statistically significant difference about the incidence of adverse reactions between the two groups (P>0.05). Conclusion: The effect of sufentanil postoperative analgesia is certain, which can inhibit the secretion of maternal CA level, and less impact on lactation and hemodynamics.