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Cytokeratin 19 regulates endoplasmic reticulum stress and inhibits ERp29 expression via p38 MAPK/XBP-1 signaling in breast cancer cells
Authors:I Fon Bambang  Huiping Li  Quek Choon Lau  Daohai Zhang
Institution:a Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
b Department of Laboratory Medicine, National University Hospital, 5 Lower Kent Ridge Rd, Singapore 119074, Singapore
c School of Life Sciences and Chemical Technology, Ngee Ann Polytechnic, Clementi Road, Singapore 599489, Singapore
Abstract:
Keywords:CK19  cytokeratin 19  ERp29  endoplasmic reticulum protein 29  p38  mitogen-activated protein kinase 14  FAK  focal adhesion kinase  Bip/GRP78  heat shock 70   kDa protein 5 (glucose-regulated protein 78   kDa)  PERK  RNA-dependent protein kinase-like ER kinase  p-eIF2α  phosphorylated eukaryotic translation initiation factor 2α
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