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HIF-1 in the inflammatory microenvironment
Authors:Nathalie Dehne
Affiliation:Institute of Biochemistry I - Pathobiochemistry / ZAFES, Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany
Abstract:
Keywords:DC, dendritic cell   FIH, factor inhibiting HIF   GLUT, glucose transporter   HIF, hypoxia-inducible factor   HRE, hypoxia-response element   IL, interleukin   IkB, inhibitor of kappa B   LPS, lipopolysaccharides   MAPK, mitogen-activated protein kinase   NF-κB, nuclear factor kappa B   NFAT, nuclear factor of activated T-cells   NO, nitric oxide   iNOS, inducible nitric oxide synthase   ODD, oxygen degradation domain   PHD, prolyl hydroxylase   PI3K, phosphatidylinositol 3-kinase   ROS, reactive oxygen species   TAM, tumor-associated macrophage   TNF, tumor necrosis factor   VEGF, vascular endothelial growth factor
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