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HIF-1 in the inflammatory microenvironment |
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| Authors: | Nathalie Dehne |
| Institution: | Institute of Biochemistry I - Pathobiochemistry / ZAFES, Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany |
| Abstract: | |
| Keywords: | DC dendritic cell FIH factor inhibiting HIF GLUT glucose transporter HIF hypoxia-inducible factor HRE hypoxia-response element IL interleukin IkB inhibitor of kappa B LPS lipopolysaccharides MAPK mitogen-activated protein kinase NF-κB nuclear factor kappa B NFAT nuclear factor of activated T-cells NO nitric oxide iNOS inducible nitric oxide synthase ODD oxygen degradation domain PHD prolyl hydroxylase PI3K phosphatidylinositol 3-kinase ROS reactive oxygen species TAM tumor-associated macrophage TNF tumor necrosis factor VEGF vascular endothelial growth factor |
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