Chemically distinct HDAC inhibitors prevent adipose conversion of subcutaneous human white preadipocytes at an early stage of the differentiation program |
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Authors: | Rose-Marie Catalioto Carlo Alberto Maggi Sandro Giuliani |
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Affiliation: | Pharmacology Department, Menarini Ricerche SpA, Via Rismondo 12A, 50131 Florence, Italy |
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Abstract: |
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Keywords: | C/EBPα, CCAAT/enhancer-binding protein-α FABP4/aP2, adipose specific fatty acid binding protein FCS, foetal calf serum GPDH, Sn-glycerol-3-phosphate dehydrogenase HBSS, Hank's balanced salt solution HDAC, histone deacetylase HDACi, histone deacetylase inhibitor LDH, lactate dehydrogenase NaBu, sodium butyrate PBS, phosphate buffered saline SAHA, suberoylanilide hydroxamic acid TSA, trichostatin A VEGF, vascular endothelial growth factor VPA, valproic acid |
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