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Chemically distinct HDAC inhibitors prevent adipose conversion of subcutaneous human white preadipocytes at an early stage of the differentiation program
Authors:Rose-Marie Catalioto  Carlo Alberto Maggi  Sandro Giuliani
Affiliation:Pharmacology Department, Menarini Ricerche SpA, Via Rismondo 12A, 50131 Florence, Italy
Abstract:
Keywords:C/EBPα, CCAAT/enhancer-binding protein-α   FABP4/aP2, adipose specific fatty acid binding protein   FCS, foetal calf serum   GPDH, Sn-glycerol-3-phosphate dehydrogenase   HBSS, Hank's balanced salt solution   HDAC, histone deacetylase   HDACi, histone deacetylase inhibitor   LDH, lactate dehydrogenase   NaBu, sodium butyrate   PBS, phosphate buffered saline   SAHA, suberoylanilide hydroxamic acid   TSA, trichostatin A   VEGF, vascular endothelial growth factor   VPA, valproic acid
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