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In vivo synthesis and processing of rat hypothalamic prosomatostatin
Authors:M Camier  N Barre  A Morel  P Cohen
Institution:Groupe de Neurobiochimie Cellulaire et Moléculaire, Université Pierre et Marie Curie, UA554 CNRS. 96 Bd. Raspail, 75006 Paris, France
Abstract:The in vivo incorporation of 3H]phenylalanine into an apparent 15 kDa prosomatostatin was observed in the hypothalamus of rats injected with the labeled amino acid in the third ventricle. Precursor-product relationships were established between this newly synthesized material and both somatostatin-28 and -14.
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