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The regulation of necroptosis and perspectives for the development of new drugs preventing ischemic/reperfusion of cardiac injury
Authors:Maslov  Leonid N.  Popov  Sergey V.  Naryzhnaya  Natalia V.  Mukhomedzyanov  Alexandr V.  Kurbatov  Boris K.  Derkachev  Ivan A.  Boshchenko  Alla A.  Khaliulin  Igor  Prasad  N. Rajendra  Singh   Nirmal  Degterev   Alexei  Tomilova   Evgenia A.  Sapozhenkova  Ekaterina V.
Affiliation:1.Cardiology Research Institute, Tomsk National Research Medical Centre, The Russian Academy of Sciences, Tomsk, Russia
;2.Institute for Drug Research, School of Pharmacy, Faculty of Medicine, Hebrew University of Jerusalem, Pharmacy Building, Ein Karem, 91120, Jerusalem, Israel
;3.Bristol Medical School (THS), Faculty of Health Sciences, University of Bristol, Bristol Royal Infirmary, Upper Maudlin Street, Bristol, BS2 8HW, UK
;4.Department of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, Tamil Nadu, India
;5.Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, India
;6.Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, MA, USA
;7.Tyumen State Medical University, Tyumen, Russia
;8.Laboratory of Experimental Cardiology, Cardiology Research Institute, Tomsk National Research Medical Center of the RAS, Kyevskaya 111A, Tomsk, Russia, 634012
;
Abstract:Apoptosis - In the last 10 years, mortality from acute myocardial infarction (AMI) has not significantly decreased. This situation is associated with the absence in clinical practice of...
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