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The regulation of necroptosis and perspectives for the development of new drugs preventing ischemic/reperfusion of cardiac injury
Authors:Maslov  Leonid N  Popov  Sergey V  Naryzhnaya  Natalia V  Mukhomedzyanov  Alexandr V  Kurbatov  Boris K  Derkachev  Ivan A  Boshchenko  Alla A  Khaliulin  Igor  Prasad  N Rajendra  Singh  Nirmal  Degterev  Alexei  Tomilova  Evgenia A  Sapozhenkova  Ekaterina V
Institution:1.Cardiology Research Institute, Tomsk National Research Medical Centre, The Russian Academy of Sciences, Tomsk, Russia
;2.Institute for Drug Research, School of Pharmacy, Faculty of Medicine, Hebrew University of Jerusalem, Pharmacy Building, Ein Karem, 91120, Jerusalem, Israel
;3.Bristol Medical School (THS), Faculty of Health Sciences, University of Bristol, Bristol Royal Infirmary, Upper Maudlin Street, Bristol, BS2 8HW, UK
;4.Department of Biochemistry and Biotechnology, Annamalai University, Annamalainagar, Tamil Nadu, India
;5.Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, India
;6.Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, MA, USA
;7.Tyumen State Medical University, Tyumen, Russia
;8.Laboratory of Experimental Cardiology, Cardiology Research Institute, Tomsk National Research Medical Center of the RAS, Kyevskaya 111A, Tomsk, Russia, 634012
;
Abstract:Apoptosis - In the last 10 years, mortality from acute myocardial infarction (AMI) has not significantly decreased. This situation is associated with the absence in clinical practice of...
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