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Evaluation of the tert-butyl group as a probe for NMR studies of macromolecular complexes
Authors:Voleti  Rashmi  Bali  Sofia  Guerrero  Jaime  Smothers  Jared  Springhower  Charis  Acosta  Gerardo A  Brewer  Kyle D  Albericio  Fernando  Rizo  Josep
Institution:1.Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA
;2.Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA
;3.Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA
;4.Center for Alzheimer’s and Neurodegenerative Diseases, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA
;5.Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA
;6.CIBER-BBN, Networking Centre on Bioengineering, Biomaterials and Nanomedicine, and Department of Organic Chemistry, University of Barcelona, 08028, Barcelona, Spain
;7.Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), Spanish National Research Council (CSIC), Jordi Girona 18-26, 08034, Barcelona, Spain
;8.Peptide Science Laboratory, School of Chemistry and Physics, University of KwaZulu-Natal, Durban, 4001, South Africa
;
Abstract:Journal of Biomolecular NMR - The development of methyl transverse relaxation optimized spectroscopy has greatly facilitated the study of macromolecular assemblies by solution NMR spectroscopy....
Keywords:
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