The cell equator - more than poles apart |
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Authors: | Dhar Pawan |
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Institution: | Systems Biology Group, Bioinformatics Institute, Matrix, 138671, Singapore. pk@bii-sg.org |
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Abstract: | Cytokinesis is the last ritual of a dividing cell. Determining the position and horizon of the cell furrow is important for equal distribution of cytoplasmic content between the two daughter cells. The traditional view promotes a classical sequence of bipolar spindle formation followed by cytokinesis. However, a new understanding has recently emerged that uncouples these events. The cell-furrow formation seems to ignore spindle polarity and is instead dependent on the stability and dynamics of cortical microtubules. |
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