Kinetic study on the enzymatic resolution of homophenylalanine ester using ionic liquids |
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Authors: | Zhao Hua Luo Robert G Malhotra Sanjay V |
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Institution: | Department of Chemistry and Environmental Science, New Jersey Institute of Technology, University Heights, Newark, New Jersey 07102, USA. |
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Abstract: | Two ionic liquids (ILs) were investigated as novel media for the enzymatic resolution of amino acid ester to obtain enantiomeric amino acid homophenylalanine. The effects of solvent nature, polarity, and concentration on the kinetic resolution were investigated. With change in solvent concentration, a systematic study shows that an improved enzyme activity can be obtained by adjusting these solvent parameters. |
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