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The production,testing, and utility of double congenic mouse strains
Authors:Peter J. Wettstein  Geoffrey Haughton
Affiliation:(1) Genetics Curriculum, Department of Bacteriology and Immunology, University of North Carolina, 27514 Chapel Hill, North Carolina;(2) Present address: Department of Microbiology, University of Southern California Medical School, 2025 Zonal Avenue, 90033 Los Angeles, California
Abstract:Two new double congenic strains, B10-H-2aH-7b/Wts and B10-H-2dH-7b/Wts, were selected to differ from B10.A and B10.D2/o, respectively, at theH-7 locus. The survival time ofH-7-incompatible skin grafts is dependent upon theH-2 haplotype of recipient and donor.
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