The production,testing, and utility of double congenic mouse strains |
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Authors: | Peter J. Wettstein Geoffrey Haughton |
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Affiliation: | (1) Genetics Curriculum, Department of Bacteriology and Immunology, University of North Carolina, 27514 Chapel Hill, North Carolina;(2) Present address: Department of Microbiology, University of Southern California Medical School, 2025 Zonal Avenue, 90033 Los Angeles, California |
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Abstract: | Two new double congenic strains, B10-H-2aH-7b/Wts and B10-H-2dH-7b/Wts, were selected to differ from B10.A and B10.D2/o, respectively, at theH-7 locus. The survival time ofH-7-incompatible skin grafts is dependent upon theH-2 haplotype of recipient and donor. |
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