Hantavirus Transmission in Sylvan and Peridomestic Environments |
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Authors: | Tomá? Gedeon Clara Bodelón Amy Kuenzi |
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Institution: | 1.Department of Mathematical Sciences,Montana State University,Bozeman,USA;2.Department of Epidemiology,University of Washington,Seattle,USA;3.Department of Biology,Montana Tech of the University of Montana,Butte,USA |
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Abstract: | We developed a compartmental model for hantavirus infection in deer mice (Peromyscus maniculatus) with the goal of comparing relative importance of direct and indirect transmission in sylvan and peridomestic environments.
A direct transmission occurs when the infection is mediated by the contact of an infected and an uninfected mouse, while an
indirect transmission occurs when the infection is mediated by the contact of an uninfected mouse with, for instance, infected
soil. Based on population dynamics data and estimates of hantavirus decay in the two types of environments, our model predicts
that direct transmission dominates in the sylvan environment, while both pathways are important in peridomestic environments.
The model allows us to compute a basic reproduction number R
0, which indicates whether the virus will be endemic or eradicated from the mouse population, in both an autonomous and a time-periodic
model. Our analysis can be used to evaluate various eradication strategies. |
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Keywords: | |
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