| 生物技术生产虾青素研究的最新进展 |
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| 引用本文： | 董庆霖,赵学明,马红武,白小佳.生物技术生产虾青素研究的最新进展[J].生物加工过程,2004,2(2):18-24. |
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| 作者姓名： | 董庆霖 赵学明 马红武 白小佳 |
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| 作者单位： | 天津大学,化工学院生物化工系,天津,300072 |
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| 基金项目： | 国家自然科学基金NSFC 2 0 0 3 60 10，国家 973计划项目No 2 0 0 3CB7160 0 3 |
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| 摘 要： | 虾青素是一种具有极强的生物抗氧化性的酮式类胡萝卜素在医药，食品，化妆品等方面有着极广阔的应用前景。对目前生物技术生产虾青素的两种主要方法：即雨生红球藻(haematococcus pluvialis)培养法和红发夫酵母(xanthopltyllomyces dendrorhous,formedy Phaffia raodazyma)发酵法的最新研究进展，包括采用的微生物的生理代谢特性、虾青素合成途径、生产技术特点、工程菌种的构建等方面进行了系统的总结。针对天然虾青素生产技术研究中存在的问题和不足，提出了建议和解决的方法。
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| 关 键 词： | 虾青素 雨生红球藻 红发夫酵母 培养 发酵 工程菌种 |
| 文章编号： | 1672-3678(2004)02-0018-07 |
| 修稿时间： | 2004年3月12日 |
Recent advances in the research of astaxanthin production through biotechnology |
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| DONG Qing-lin,ZHAO Xue-ming,MA Hong-wu,BAI Xiao-jia.Recent advances in the research of astaxanthin production through biotechnology[J].Chinese Journal of Bioprocess Engineering,2004,2(2):18-24. |
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| Authors: | DONG Qing-lin ZHAO Xue-ming MA Hong-wu BAI Xiao-jia |
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| Abstract: | Astaxanthin is a kind of ketocarotenoid with strong biological antioxidant activities, which is getting widely used in nutraceutical, food and cosmetic industries. The research progress of the two main natural astaxanthin production techniques: haematococcus pluvialis cultivation and phaffia rhodozyma (xanthophyllomyces dendrorhous) fermentation was summarized systematically in this article, including the physiological and metabolic characteristics, astaxanthin synthesis pathway, production technology, construction of engineered genus. Furthermore, a new strategy was proposed to deal with the problems emerged in the research of natural astaxanthin production. |
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| Keywords: | astaxanthin haematococcus pluvialis phaffia rhodozyma cultivation fermentation engineered genus |
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