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Gene markers for alcohol-metabolizing enzymes among recombinant inbred strains of mice with differential behavioural responses towards alcohol
Authors:R. S. Holmes   P. B. Mather  J. A. Duley
Affiliation:School of Science, Griffith University, Nathan, Qld 4111, Australia
Abstract:The genetic variability of alcohol dehydrogenase (C2 isozyme), aldehyde dehydrogenase (A2 isozyme) and aldehyde oxidase (A2 isozyme) has been examined among recombinant inbred strains of mice which have been previously studied concerning their differential behavioural responses towards alcohol. The results showed no correlation between biochemical phenotype for these loci and behavioural response.
Keywords:mouse    alcohol dehydrogenase    aldehyde dehydrogenase    recombinant inbred strains    behavioural responses    alcohol
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