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A Non-canonical BRCT-Phosphopeptide Recognition Mechanism Underlies RhoA Activation in Cytokinesis
Affiliation:1. Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA;2. Section of Cell and Developmental Biology, Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA;3. Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093, USA;4. Small Molecule Discovery Program, Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA
Abstract:
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  • Keywords:cytokinesis  cell division  RhoA  small GTPase  MgcRacGAP  RACGAP1  centralspindlin  Plk1  Ect2  BRCT domain
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