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Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling
Institution:1. Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada;2. Department of Physiology and Medical Physics, Medical University of Innsbruck, 6020 Innsbruck, Austria
Abstract:
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  • Keywords:muscle excitation-contraction coupling  calcium channel  calcium signaling  calorimetry  X-ray crystallography  myopathy  genetic disorder  Ryanodine Receptor  molecular dynamics
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