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Furoquinoline alkaloids from Teclea nobilis
Authors:Al-Rehaily Adnan J  Ahmad Mohammad S  Muhammad Ilias  Al-Thukair Assad A  Perzanowski Herman P
Affiliation:Department of Pharmacognosy, College of Pharmacy, King Saud University, 11451, Riyadh, Saudi Arabia. ajalreha@ksu.edu.sa
Abstract:Five new furoquinoline alkaloids, namely tecleabine (1), tecleoxine (2), isotecleoxine (3), methylnkolbisine (4) and chlorodesnkolbisine (5) were isolated from the aerial parts of Teclea nobilis, together with seven known furoquinoline derivatives; one acridone alkaloid, and one known flavanone. The structures of the alkaloids 1-5 were established by 1D and 2D NMR spectral data, including COSY, HMQC and HMBC experiments, as well as HRMS.
Keywords:Teclea nobilis   Rutaceae   Alkaloids   Furoquinoline   Tecleabine   Tecleoxine   Isotecleoxine   Methylnkolbisine   Chlorodesnkolbisine
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