Institution: | From the ‡Department of Medical Chemistry, Graduate School of Medicine, Kyoto University, Yoshida-Konoe, Sakyo-ku, Kyoto 606-8501.;the §Graduate School of Frontier Biosciences, Osaka University, Osaka 565-0871, and ;the ¶Core Research for Evolutional Science and Technology, Japan Science and Technology Corporation, Saitima 332-0012, Japan |