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A New Mode of Mineralocorticoid Receptor Antagonism by a Potent and Selective Nonsteroidal Molecule |
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| Authors: | Jér?me Fagart Alexander Hillisch Jessica Huyet Lars B?rfacker Michel Fay Ulrich Pleiss Elisabeth Pook Stefan Sch?fer Marie-Edith Rafestin-Oblin Peter Kolkhof |
| Affiliation: | From the Departments of ¶Medicinal Chemistry.;‖Isotope Chemistry.;**Lead Discovery, and ;‡‡Cardiology Research, Bayer Schering Pharma AG, Global Drug Discovery, 42096 Wuppertal, Germany.;‡INSERM U773, Centre de Recherche Biomédicale Bichat-Beaujon, CRB3, 75870 Paris, France, and ;the §Université Paris 7-Denis Diderot, Site Bichat, 75018 Paris, France |
| Abstract: | |
| Keywords: | Drug Action Drug Design Heart Kidney Steroid Hormone Receptor Cardiovascular Diseases Drug Discovery Mechanism of Action Steroid Receptors Antagonist |