Differential stimulation of second messenger pathways by distinct classes of odorants |
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Authors: | I. Boekhoff H. Breer |
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Affiliation: | University Stuttgart-Hohenheim, Department of Zoophysiology, Garbenstraße 30, 7000, Stuttgart 70, F.R.G. |
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Abstract: | Using ciliary preparations from rat olfactory epithelia, representative compounds of different odorant classes were assayed for the capability of stimulating the formation of second messengers in a subsecond time range. Fruity, floral and minty odors were found to induce a transient accumulation of cyclic adenosine monophosphate, whereas the herbaceous and putrid compounds under test caused a rise in inositol trisphosphate concentration. |
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