Sensitivity of bacterial coaggregation to chelating agents |
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Authors: | Taweechaisupapong S Doyle R J |
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Affiliation: | Faculty of Dentistry, Khon Kaen University, Thailand. |
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Abstract: | Coaggregation between pairs of microorganisms was found to be inhibited by chelating agents, such as acetylacetone, citrate, EDTA and carboxymethylcellulose. Assays were conducted on eight pairs of periodontopathogens and one pair consisting of Escherichia coli and Saccharomyces cerevisiae. The inhibitory effects of the chelating agents were reversible except for Actinomyces naeslundii 12104, the adhesin of which was irreversibly inactivated. Even though the bacteria possessed different kinds of adhesins, their sensitivity to chelating agents appears to be a common property. Non-toxic chelating agents, such as carboxymethylcellulose and citrate, may prove to be useful anti-adhesins. |
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Keywords: | Lectin Chelate Adhesin Coaggregation Periodontopathogen |
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