Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies

Affiliation:	3. Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada;4. Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Canada;5. Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada;6. Department of Clinical Biochemistry, University Health Network, Toronto, Canada

Abstract:	Download : Download high-res image (105KB) Download : Download full-size image Highlights •Quantitative co-IP-MS approach to discover the human TEX101 interactome. •Validation of the human testis-specific protein complex TEX101-DPEP3. •Development of a hybrid immunoassay to screen for disruptors of TEX101-DPEP3 complex.

Keywords:	Protein-Protein Interactions Antibodies Affinity proteomics Immunoaffinity Label-free quantification Mass Spectrometry Targeted mass spectrometry Tandem Mass Spectrometry DPEP3 interactome spermatozoa testis-specific proteins TEX101
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