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Identification of Novel Response and Predictive Biomarkers to Hsp90 Inhibitors Through Proteomic Profiling of Patient-derived Prostate Tumor Explants
Affiliation:3. Cancer Program, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia;;4. Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia;;5. Adelaide Medical School and Freemasons Foundation Centre for Men''s Health, University of Adelaide, Adelaide, South Australia 5005, Australia;;6. South Australian Health and Medical Research Institute, Adelaide, South Australia 5000, Australia;;12. Royal Prince Alfred Hospital, Camperdown, New South Wales 2050, Australia;;8. Department of Medical Oncology, Chris O''Brien Lifehouse, Camperdown, New South Wales 2050, Australia;;9. School of Medicine, Flinders University, Bedford Park, SA 5042, Australia
Abstract:
Keywords:Prostate cancer biomarkers  Patient cohorts  Cancer therapeutics  Tumor microenvironment  Biomarker: Diagnostic  Biomarker: Prognostic  ex vivo  Hsp90 inhibitors  patient-derived explants
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