N-terminal Acetylation Levels Are Maintained During Acetyl-CoA Deficiency in Saccharomyces cerevisiae期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

N-terminal Acetylation Levels Are Maintained During Acetyl-CoA Deficiency in Saccharomyces cerevisiae

Affiliation:	3. Department of Biomedicine, University of Bergen, N-5020 Bergen, Norway;4. Department of Biological Sciences, University of Bergen, N-5020 Bergen, Norway;5. Donnelly Center for Cellular and Bio3molecular Research, University of Toronto, Toronto, ON M5S 3E1, Canada;6. VIB-UGent Center for Medical Biotechnology, B-9000 Ghent, Belgium;12. VIB Proteomics Core, B-9000 Ghent, Belgium;8. Department of Surgery, Haukeland University Hospital, N-5021 Bergen, Norway

Abstract:	Download : Download high-res image (84KB) Download : Download full-size image Highlights •First global study on metabolic regulation of Nt-acetylation. •Yeast cells maintain global Nt-acetylation levels during prolonged starvation. •Nt-acetylation can in some cases be either up- or downregulated by starvation. •Naa10/NatA affects the steady-state protein levels of Rsa3 and Rpl7a.

Keywords:	Acetylation Molecular biology N-terminal modifications Tandem Mass Spectrometry Yeast Acetyl coenzyme A Metabolism N-terminal acetylation N-terminomics Ribosomal proteins
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