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Evaluation of microarray data normalization procedures using spike-in experiments |
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| Authors: | Patrik Rydén Henrik Andersson Mattias Landfors Linda Näslund Blanka Hartmanová Laila Noppa Anders Sjöstedt |
| Institution: | 1. Department of Clinical Microbiology Division of Clinical Bacteriology, Ume? University, SE-90187, Ume?, Sweden 2. Department of Mathematics and Mathematical Statistics, Ume? University, SE-90187, Ume?, Sweden 3. Proteome Center for the Study of Intracellular Parasitism of Bacteria, Faculty of Military Health Science, University of Defence, Trebesská 1575, 50001, Hradec Králové, Czech Republic 4. Department of Medical Countermeasures, Division of NBC-Defence, Swedish Defence Research Agency, SE-90182, Ume?, Sweden |
| Abstract: | BackgroundRecently, a large number of methods for the analysis of microarray data have been proposed but there are few comparisons of their relative performances. By using so-called spike-in experiments, it is possible to characterize the analyzed data and thereby enable comparisons of different analysis methods. |
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