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Stochastic modeling of oligodendrocyte generation in cell culture: model validation with time-lapse data |
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| Authors: | Ollivier Hyrien Ibro Ambeskovic Margot Mayer-Proschel Mark Noble Andrei Yakovlev |
| Institution: | (1) Department of Biostatistics and Computational Biology, University of Rochester, 601 Elmwood Avenue, 14642 Rochester, New York, USA;(2) Department of Biomedical Genetics, University of Rochester, 601 Elmwood Avenue, 14642 Rochester, New York, USA |
| Abstract: | BackgroundThe purpose of this paper is two-fold. The first objective is to validate the assumptions behind a stochastic model developed earlier by these authors to describe oligodendrocyte generation in cell culture. The second is to generate time-lapse data that may help biomathematicians to build stochastic models of cell proliferation and differentiation under other experimental scenarios. |
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