Effect of transverse gap-junction channels on transverse propagation in an enlarged PSpice model of cardiac muscle |
| |
| Authors: | Lakshminarayanan Ramasamy Nicholas Sperelakis |
| |
| Affiliation: | (1) Dept. of Electrical Computer Engineering and Computer Science, University of Cincinnati College of Engineering, 45219 Cincinnati, OH, USA;(2) Dept. of Molecular & Cellular Physiology, University of Cincinnati College of Medicine, 45267-0576 Cincinnati, OH, USA |
| |
| Abstract: | Background In previous PSpice modeling studies of simulated action potentials (APs) in parallel chains of cardiac muscle, it was found that transverse propagation could occur between adjacent chains in the absence of gap-junction (gj) channels, presumably by the electric field (EF) generated in the narrow interstitial space between the chains. Transverse propagation was sometimes erratic, the more distal chains firing out of order. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
