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Quality control for terms and definitions in ontologies and taxonomies |
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| Authors: | Jacob Köhler Katherine Munn Alexander Rüegg Andre Skusa Barry Smith |
| Affiliation: | 1. Biomathematics and Bioinformatics Division, Rothamsted Research, Harpenden, UK 3. Institute for Formal Ontology and Medical Information Science, Saarland University, Saarbrücken, Germany 4. Technical Faculty, Bielefeld University, Bielefeld, Germany 2. Department of Philosophy, University at Buffalo, NY, USA |
| Abstract: | BackgroundOntologies and taxonomies are among the most important computational resources for molecular biology and bioinformatics. A series of recent papers has shown that the Gene Ontology (GO), the most prominent taxonomic resource in these fields, is marked by flaws of certain characteristic types, which flow from a failure to address basic ontological principles. As yet, no methods have been proposed which would allow ontology curators to pinpoint flawed terms or definitions in ontologies in a systematic way. |
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