Identification and evolutionary analysis of novel exons and alternative splicing events using cross-species EST-to-genome comparisons in human, mouse and rat |
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Authors: | Feng-Chi Chen Chuang-Jong Chen Jar-Yi Ho Trees-Juen Chuang |
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Institution: | (1) Genomics Research Center, Academia Sinica, Academia Road, Nankang, Taipei, 11529, Taiwan |
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Abstract: | Background Alternative splicing (AS) is important for evolution and major biological functions in complex organisms. However, the extent
of AS in mammals other than human and mouse is largely unknown, making it difficult to study AS evolution in mammals and its
biomedical implications. |
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Keywords: | |
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