Use of a multilocus variable-number tandem repeat analysis method for molecular subtyping and phylogenetic analysis of Neisseria meningitidis isolates |
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Authors: | Jui-Cheng Liao Chun-Chin Li Chien-Shun Chiou |
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Institution: | (1) The Third Branch Office, Center for Disease Control, 408 Taichung, Taiwan |
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Abstract: | Background The multilocus variable-number tandem repeat (VNTR) analysis (MLVA) technique has been developed for fine typing of many bacterial
species. The genomic sequences of Neisseria meningitidis strains Z2491, MC58 and FAM18 have been available for searching potential VNTR loci by computer software. In this study,
we developed and evaluated a MLVA method for molecular subtyping and phylogenetic analysis of N. meningitidis strains. |
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