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Changes in the efficacy of transmission at synapses of the dorsal horn of the cat spinal cord observed during repetitive activation of cutaneous afferents
Authors:D A Rusakov  O A Shugurov
Abstract:Inhibitory patterns in monosynaptic components of field potentials and potentials in the dorsal spinal cord surface were investigated during acute experiments on cats involving low-frequency stimulation of cutaneous peripheral nerves. Approximation of experimental data obtained from a theoretical plot was performed adopting a standard model of transmitter storage and release. Parameters of fractional release and replenishment of transmitter depleted from synaptic junctions were determined. Processes of replenishing supplies of transmitter for release were seen to intensify under rhythmic stimulation. A comparison between these experimental findings on the character of synapses of the monosynaptic reflex arc and others found in the literature indicated a similarity between the parameters of the mechanism underlying transmitter mobilization and release at different synaptic junctions formed by primary afferent fibers.Dnepropetrovsk State University Commemorating the 300th Aniversary of Ukraine-Russian Reunion, Dnepropetrovsk. Translated from Neirofiziologiya, Vol. 19, No. 4, pp. 491–497, July–August, 1987.
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