Genome-wide differential expression of long noncoding RNAs and mRNAs in ovarian follicles of two different chicken breeds |
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| Institution: | 1. College of Animal Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao 066004, Hebei, People''s Republic of China;2. College of Animal Science and Technology, Agricultural University of Hebei Province, Baoding 071001, Hebei, People''s Republic of China;3. College of Life Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao 066004, Hebei, People''s Republic of China;4. Qinhuangdao Animal Disease Control Center, Qinhuangdao 066001, Hebei, People''s Republic of China. |
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| Abstract: | Bashang long-tail chickens are an indigenous breed with dual purpose in China (meat and eggs) but have low egg laying performance. To improve the low egg laying performance, a genome-wide analysis of mRNAs and long noncoding RNAs (lncRNAs) from Bashang long-tail chickens and Hy-Line brown layers was performed. A total of 16,354 mRNAs and 8691 lncRNAs were obtained from ovarian follicles. Between the breeds, 160 mRNAs and 550 lncRNAs were found to be significantly differentially expressed. Integrated network analysis suggested some differentially expressed genes were involved in ovarian follicular development through oocyte meiosis, progesterone-mediated oocyte maturation, and cell cycle. The impact of lncRNAs on cis and trans target genes, indicating some lncRNAs may play important roles in ovarian follicular development. The current results provided a catalog of chicken ovarian follicular lncRNAs and genes for further study to understand their roles in regulation of egg laying performance. |
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