Diversity and functions of glycosaminoglycan sulfotransferases |
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| Authors: | Habuchi O |
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| Institution: | Department of Life Science, Aichi University of Education, Kariya, Aichi, Japan. ohabuchi@auecc.aichi-edu.ac.jp |
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| Abstract: | Sulfate residues attached to the specific position of the component sugar residues of glycosaminoglycans play important roles in the formation of functional domain structures. The introduction of a sulfate group is catalyzed by various sulfotransferases with strict substrate specificities. A rapid development achieved in the cloning of various glycosaminoglycan sulfotransferases has allowed us to study the biological functions of glycosaminoglycan sulfotransferases and their products, sulfated glycosaminoglycans. |
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