The sources of genetic variability in highly inbred long-term selected strains of Drosophila melanogaster |
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| Authors: | L Z Kaidanov V N Bolshakov P N Tzygvintzev V A Gvozdev |
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| Institution: | (1) Department of Genetics and Breeding, Leningrad State University, 199034 Leningrad, USSR;(2) Institute of Molecular Genetics, USSR Academy of Sciences, 123182 Moscow, USSR |
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| Abstract: | A highly inbred, long-term selected for low fitness strain LA of Drosophila melanogaster posesses a significant mutational load and unusually high rates of spontaneous mutability as revealed by CyL/Pm method. Our results indicate that during cross of CyL/Pm to LA strains, destabilization of copia-like and mobile elements and induction of H-E hybrid dysgenesis take place. The role of these processes in causing considerable genetic variability of LA strain is discussed. |
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