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Constituents from the pseudofruits of Hovenia dulcis and their chemotaxonomic significance
Affiliation:1. College of Pharmacy, Drug Research and Development Center, Daegu Catholic University, Gyeongbuk, 38430, Republic of Korea;2. School of Pharmacy, Sungkyunkwan University, Suwon, 16419, Republic of Korea;3. Department of Biopharmaceutical Convergence, Sungkyunkwan University, Suwon, 16419, Republic of Korea;4. Department of Biochemistry, College of Natural Sciences, Kangwon National University, Chuncheon, Gangwon-Do, 24341, Republic of Korea;5. College of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, 41566, Republic of Korea
Abstract:Sixteen compounds, including six flavonoids (16), one lignan (7), three megastigmanes (810), three triterpenoids (1113), and three benzoic acid derivatives (1416) were isolated and structurally elucidated from the pseudo-fruits of Hovenia dulcis. Their structures were analyzed by NMR spectroscopic and data comparison. Among them, compounds 4, 711, 13, 15, and 16 were isolated from the Hovenia genus for the first time. The chemotaxonomic significance of the isolates was also described, which revealed a relationship between H. dulcis and H. acerbar as well as other species belonging to the Rhamnaceae family.
Keywords:Rhamnaceae  Megastigmane  Triterpenoid  Flavonoid
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